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Index > Protein center > Ece1(Gene name) > Rat
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  • Ece1 (Gene name),
  • Endothelin-converting enzyme 1 (Protein name ),  ECE1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ece1;
    Protein name:
    Endothelin-converting enzyme 1(ECE-1);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Converts big endothelin-1 to endothelin-1.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    762
    Sequence:
    50:
    MGSLRPPQGL | GLQWSSFFLG | KKGPGLTVSL | PLLASSLQVN | FRSPRSGQRC | 
    100:
    WAARTSVEKR | LVVLVTLLAA | GLVACLAALG | IQYRTRTPPV | CLTEACVSVT | 
    150:
    SSILNSMDPT | VDPCQDFFSY | ACGGWIKANP | VPDGHSRWGT | FSNLWEHNQA | 
    200:
    IIKHLLENST | ASASEAEKKA | QVYYRACMNE | TRIEELRAKP | LMELIEKLGG | 
    250:
    WNITGPWAKD | NFQDTLQVVT | AHYRTSPFFS | VYVSADSKNS | NSNVIQVDQS | 
    300:
    GLGLPSRDYY | LNKTENEKVL | TGYLNYMVQL | GKLLGGGDED | SIRPQMQQIL | 
    350:
    DFETALANIT | IPQEKRRDEE | LIYHKVTAAE | LQTLAPAINW | LPFLNAIFYP | 
    400:
    VEINESEPIV | VYDKEYLRQV | STLINSTDKC | LLNNYMMWNL | VRKTSSFLDQ | 
    450:
    RFQDADEKFM | EVMYGTKKTC | LPRWKFCVSD | TENNLGFALG | PMFVKATFAE | 
    500:
    DSKNIASEII | LEIKKAFEES | LSTLKWMDED | TRRSAKEKAD | AIYNMIGYPN | 
    550:
    FIMDPKELDK | VFNDYTAVPD | LYFENAMRFF | NFSLRVTADQ | LRKAPNRDQW | 
    600:
    SMTPPMVNAY | YSPTKNEIVF | PAGILQAPFY | TRSSPNALNF | GGIGVVVGHE | 
    650:
    LTHAFDDQGR | EYDKDGNLRP | WWKNSSVEAF | KQQTECMVQQ | YNNYSVNGEP | 
    700:
    VNGRHTLGEN | IADNGGLKAA | YRAYQNWVKK | NGAEQILPTL | GLTSNQLFFL | 
    750:
    GFAQVWCSVR | TPESSHEGLI | TDPHSPSRFR | VIGSLSNSKE | FSEHFRCPLG | 
    762:
    SPMNPRHKCE | VW
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat ECE-1
    Cat.:
    E9194m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat ECE-1
    Cat.:
    E9194r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat ECE-1
    Cat.:
    E9194b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat ECE-1
    Cat.:
    E9194h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat ECE-1
    Cat.:
    U9194r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat ECE-1
    Cat.:
    U9194m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat ECE-1
    Cat.:
    U9194b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat ECE-1
    Cat.:
    U9194h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat ECE-1
    Polyclonal Antibody for Rat ECE-1
    Cat.:
    P9194Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat ECE-1
    Cat.:
    P9194Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat ECE-1
    Monoclonal Antibody for Rat ECE-1
    Monoclonal Antibody for Rat ECE-1
    Monoclonal Antibody for Rat ECE-1
    Monoclonal Antibody for Rat ECE-1
    Protein for Rat ECE-1
    Protein for Rat ECE-1
    Protein for Rat ECE-1
    Protein for Rat ECE-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells."
      Shimada K. , Takahashi M. , Tanzawa K.
      J. Biol. Chem.269:18275-18278(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM C)
      tissue: Endothelial cell.
    2. 2.
      "A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter."
      Valdenaire O. , Lepailleur-Enouf D. , Egidy G. , Thouard A. , Barret A. , Vranckx R. , Tougard C. , Michel J.-B.
      Eur. J. Biochem.264:341-349(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-116;ALTERNATIVE SPLICING;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Smooth muscle.
    3. 3.
      "Identification and characterization of two isoforms of an endothelin-converting enzyme-1."
      Shimada K. , Takahashi M. , Ikeda M. , Tanzawa K.
      FEBS Lett.371:140-144(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-109 (ISOFORM A)
      strain: Sprague-Dawley.
      tissue: Lung.
    4. 4.
      "Rat endothelin-converting enzyme-1 forms a dimer through Cys412 with a similar catalytic mechanism and a distinct substrate binding mechanism compared with neutral endopeptidase-24.11."
      Shimada K. , Takahashi M. , Turner A.J. , Tanzawa K.
      Biochem. J.315:863-867(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;SUBCELLULAR LOCATION;MUTAGENESIS OF CYS-420; GLU-600; GLU-659 AND HIS-724
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